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目的 对以西艾克为主联合化疗治疗中晚期恶性肿瘤的疗效对比研究。方法 以西艾克为主联合化疗方案治疗肺癌、淋巴瘤、乳腺癌、胃癌和结、直肠癌、子宫颈癌、肺转移癌、睾丸精原细胞瘤。结果 总有效率为58.5％,其中肺癌有效率为43.7％,恶性淋巴瘤有效率为80.0％,乳腺癌有效率为75.0％,初治病例有效率为53.3％。结论 西艾克联合化疗对多种恶性肿瘤有效,特别是乳腺癌及化疗效果差的非小细胞肺癌中的肺腺癌有明显疗效。神经毒性轻微,骨髓抑制是其剂量限制性毒性。
Objective To compare the efficacy of using West-aiker-based chemotherapy in the treatment of advanced malignant tumors. Methods The treatment of lung cancer, lymphoma, breast cancer, gastric cancer, and colorectal cancer, cervical cancer, metastatic lung cancer, and testicular seminoma were performed in combination with chemotherapy based on West AEC. Results The total effective rate was 58.5%, of which the effective rate of lung cancer was 43.7%, the effective rate of malignant lymphoma was 80.0%, the effective rate of breast cancer was 75.0%, and the effective rate of initial treatment was 53.3%. Conclusions Si Aik combined with chemotherapy is effective for a variety of malignant tumors, especially for lung adenocarcinoma in breast cancer and non-small cell lung cancer with poor chemotherapy effect. Neurotoxicity is mild and myelosuppression is its dose-limiting toxicity.