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目的研究分析妊娠合并重度血小板减少症患者的患病原因,并总结临床处理对策,以提高临床治疗妊娠合并重度血小板减少症的效果。方法选取53例妊娠合并重度血小板减少症患者为观察组,同期在我院生产的70例健康孕妇为对照组,分析比较两组孕妇的血小板计数、产后出血量及产后的不良结局。结果妊娠合并重度血小板减少的病因主要为特发性血小板减少性紫癜(ITP)、再生障碍性贫血、白血病、妊娠期高血压等。观察组的血小板计数低于对照组(P<0.05);观察组的产后出血量高于对照组(P<0.05);观察组的产后不良结局高于对照组(P<0.05),具有统计学意义。结论论孕妇在妊娠期合并重度血小板减少症的病因很多,而且愈后多不良,主治医师一定要及时检查出患者的病因,并采取针对性的治疗方法。
Objective To study the causes of pregnancy with severe thrombocytopenia and to summarize the clinical treatment strategies to improve the clinical efficacy of treatment of severe thrombocytopenia in pregnancy. Methods Fifty-three pregnant women with severe thrombocytopenia were selected as observation group and 70 healthy pregnant women in our hospital during the same period as control group. The platelet count, postpartum hemorrhage and postpartum adverse outcomes were compared between the two groups. Results The main causes of severe thrombocytopenia in pregnancy were idiopathic thrombocytopenic purpura (ITP), aplastic anemia, leukemia and gestational hypertension. The platelet count in the observation group was lower than that in the control group (P <0.05), and the postpartum hemorrhage volume in the observation group was higher than that in the control group (P <0.05). The adverse postpartum outcomes in the observation group were higher than those in the control group (P <0.05) significance. Conclusions The causes of severe thrombocytopenia in pregnant women complicated by thrombocytopenia are many, and the prognosis is poor. The attending physician must promptly check out the cause of the patients and take targeted treatment.