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为观察硒对支原体（MP）肺炎的治疗效果，采用双盲随机对照实验设计，选择100例住院支原体肺炎患儿，分为补硒组56例，以及病例对照组44例，正常组21例。一次补充硒的剂量为1毫克亚硒酸钠，对照病例组则给予常规治疗。结果表明，与对照组相比，治疗后补硒组的部分症状和体征缓解天数有所缩短（T＝2．75和2．17，P＜0．05），补硒组白细胞硒和谷胱甘肽过氧化物酶（GSH－PX）水平显著上升（F＝22．879，8．999，P＜0．05），细胞免疫功能有所改善。结果提示，补充硒作为辅助治疗支原体肺炎可能有帮助。
In order to observe the therapeutic effect of selenium on mycoplasma pneumoniae, 100 children with mycoplasmal pneumonia were selected as double-blind randomized controlled trial. They were divided into selenium-supplemented group (56 cases), case-control group (44 cases) and normal group (21 cases). One dose of selenium supplementation was 1 mg sodium selenite, while the control case group was given routine treatment. The results showed that compared with the control group, the number of symptom-relieving days and the number of days of symptom relief in the selenium group were shortened (T = 2.75 and 2.17, P <0.05), selenium and selenium The level of GSH-PX increased significantly (F = 22.879, 8.999, P <0.05), and cellular immune function was improved. The results suggest that supplementation of selenium as a supplementary treatment of mycoplasma pneumonia may be helpful.