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目的探讨坦索罗辛对肾结石体外冲击波碎石(ESWL)术后排石疗效及分析。方法 240例单纯肾结石患者行ESWL术后随机分为坦索罗辛及对照两组,均给予排石冲颗粒及氟罗沙星。坦索罗辛组120例,给予坦索罗辛(哈乐),治疗时间4周,比较两组之间结石排净率、石街的形成、疼痛评分(VAS)、膀胱刺激症状。结果坦索罗辛组的结石排净率高于对照组;坦索罗辛组石街形成率)、疼痛VAS评分及膀胱刺激症状发生率均低于对照组。治疗期间两组未出现药物不良反应。结论 ESWL术后坦索罗辛能够促进ESWL术后结石排出,预防石街形成,缓解疼痛及膀胱刺激症状,可以作为肾结石ESWL术后排石的辅助用药。
Objective To investigate the effect of tamsulosin on stone rowing after kidney stone extracorporeal shock wave lithotripsy (ESWL). Methods Two hundred and forty patients with simple nephrolithiasis were randomly divided into tamsulosin and control group after ESWL and were given Paishi Chong granules and fleroxacin. Tamsulosin group, 120 patients were given tamsulosin (Harmony). The treatment time was 4 weeks. The stone clearance rate, stone street formation, pain score (VAS) and bladder irritation were compared between the two groups. Results The tamsulosin group had a higher rate of stone removal than that of the control group; the stone street formation rate of tamsulosin group), the pain VAS score and the incidence of bladder irritation were lower than those of the control group. Two groups did not appear adverse drug reaction during treatment. Conclusion Tamsulosin after ESWL can promote the stone discharge after ESWL, prevent stone street formation, relieve the pain and irritation of the bladder. It can be used as adjuvant therapy for stone row after ESWL.