肝细胞生长因子 (HGF)是一种高效的多效性因子 ,对多种器官的不同类型细胞均有多种生物学作用。HGF对于肾脏的发生、形成、修复及肾脏病理过程有重要作用 ,在急性肾衰竭 (ARF)时HGF具有促进肾小管修复及肾脏再生 ,降低死亡率 ,缩短病程的作用 ;在各种慢性肾脏疾病的发生发展中具有重要的调节作用。 Hepatocyte growth factor (HGF) is an efficient pleiotropic factor that has multiple biological effects on different cell types in many organs. HGF plays an important role in the development, formation, repair and pathological process of kidney. HGF can promote renal tubular repair and renal regeneration, reduce mortality and shorten the course of disease in acute renal failure (ARF). In a variety of chronic kidney diseases The occurrence and development of an important regulatory role.