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目的了解广东地区儿童麻疹免疫水平,客观评价人群麻疹免疫状况,为调整策略并改进工作提供依据。方法采取分层整群抽样法抽取南海、盐田、饶平、乳源、德庆、遂溪6个县4个年龄组1 376名儿童,对其麻疹抗体水平进行检测。结果6个地区麻疹IgG抗体总阳性率为96.9%,麻疹IgG抗体总保护率为80.2%,总抗体几何平均浓度(GMC)为1 515mIU/ml;不同地区儿童麻疹抗体阳性率、保护率和抗体几何平均浓度(GMC)均有显著性差异;年龄别儿童麻疹抗体阳性率差异无显著性,但麻疹保护率和抗体几何平均浓度(GMC)存在显著性差异;外地与本地儿童麻疹抗体阳性率、保护率和抗体几何平均浓度(GMC)均显示无显著性差异。结论结果显示调查地区抗体总阳性率维持高水平,但珠江三角洲经济发达地区常规免疫工作质量要好于非珠江三角洲经济欠发达地区;麻疹复种工作可有效减少免疫空白儿童,维持人群麻疹高免疫水平;居住时间较长的流动儿童可以获得高的麻疹免疫水平,结合麻疹发病情况,需重点关注居住时间较短的流动儿童免疫状况。
Objective To understand the measles immunity of children in Guangdong and to evaluate the immunization status of measles in the population objectively to provide the basis for adjusting strategies and improving the work. Methods A total of 1 376 children aged 4 years in 6 counties of South China Sea, Yantian, Raoping, Ruyuan, Deqing and Suixi were collected by stratified cluster sampling method to detect the antibody level of measles. Results The total positive rate of measles IgG antibody was 96.9% in 6 regions, the total protection rate of measles IgG antibody was 80.2% and the total antibody geometric mean concentration (GMC) was 1 515mIU / ml. The positive rate, protective rate and antibody of measles antibody in children in different regions (GMC). There was no significant difference in the positive rate of measles antibody between children and adolescents, but there was a significant difference between measles protection rate and geometric mean antibody concentration (GMC). The positive rates of measles antibody, There was no significant difference between the protection rate and the geometric mean antibody concentration (GMC). Conclusions The results showed that the total positive rate of antibodies in the surveyed areas maintained a high level, but the quality of routine immunization in the economically developed Pearl River Delta was better than that in the economically underdeveloped areas in the non-Pearl River Delta. The measles replanting work could effectively reduce immunized blank children and maintain the high level of measles immunity. Floating children with longer living time can get a high level of measles immunity. Combined with the incidence of measles, the need to focus on the immune status of migrant children with shorter living time.