1 实验材料 动物:大鼠为Wistar种,由黑龙江中医药大学实验动物中心提供。药物:菊荷冲剂由实验室自制。维生素E烟酸酯胶囊:哈尔滨制药六厂生产。高脂饲料组成:10％胆固醇、0.5％胆酸、0.2％甲基硫氧嘧啶、10％猪油、83％基础饲料。2 实验方法 选取雄性大鼠60只,体重120～150g,禁食不禁水1夜,第2d晨静脉采血,分别测定各项血脂指标正常值。根据血脂水平进行分组,随机分为6组。正常对照组用基础饲料 1 Experimental materials Animals: Rats were Wistar species, provided by the Experimental Animal Center of Heilongjiang University of Chinese Medicine. Drugs: Chrysanthemum powder is homemade by the laboratory. Vitamin E nicotinate capsules: Harbin Pharmaceutical Factory 6 production. High-fat diet composition: 10% cholesterol, 0.5% cholic acid, 0.2% methyl thiouracil, 10% lard, 83% basal feed. 2 experimental methods 60 male rats were selected, weighing 120 ~ 150g, fasting can not help but water 1 night, the first 2d morning blood collection, respectively, the determination of the normal values ​​of blood lipids. Grouped according to blood lipid levels and randomly divided into 6 groups. Normal control group used basic feed