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目的:评价唐美含片对2型糖尿病的降糖作用。方法:2型糖尿病病人31人,男性21人,女性10例。年龄52.96±2.54(25～83)岁,病程13±2.75年。所有患者均合理控制饮食,已使用其他降糖药物者,均维持原来方法。在此基础上给与唐美含片每日4片,分4次含服(三餐前30分钟及睡前)。病人在用药前即用药1个月结束时,检测空腹血糖(FBS)、餐后2小时血糖、血清C肽(空腹)、血清胰岛素(空腹)、血常规、肝肾功能、血脂等主要项目。与用药前对照,进行自身对比。结果:病人服药后血常规、肝肾功能无变化;空腹血糖、餐后2小时血糖下降(P<0.01)总有效率达到61.3%;血清C肽(空腹)、血清胰岛素(空腹)、血脂未见显著变化。结论:唐美含片对2型糖尿病能有效地控制和降低血糖,无明显毒副作用。
OBJECTIVE: To evaluate the hypoglycemic effect of Tangmeiban Tablet on type 2 diabetes mellitus. Methods: 31 type 2 diabetic patients, 21 males and 10 females. Age 52.96 ± 2.54 (25 ~ 83) years old, duration of 13 ± 2.75 years. All patients have a reasonable diet, who have used other hypoglycemic agents, are to maintain the original method. On this basis to give Tang Meibong tablets daily 4, sub-4 sub-service (30 minutes before meals and before going to bed). Patients at the end of the first month of treatment, the main items of fasting blood glucose (FBS), 2 hours postprandial blood glucose, serum C-peptide (fasting), serum insulin (fasting), blood, liver and kidney function, blood lipids. Compared with the control before treatment, self-contrast. Results: After taking the medicine, the blood routine and liver and kidney function did not change. The fasting blood glucose and blood sugar decreased 2 hours postprandial (P <0.01), and the total effective rate reached 61.3%. The serum C peptide, fasting insulin, See significant changes. Conclusion: Tangmeiban tablet can effectively control and lower blood sugar in type 2 diabetes mellitus without obvious side effects.