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1982年3月5日至5月10日,对予东四县农村16万人口地区调查先天性眼球发育不全(包括无眼球、小眼球、小角膜、葡萄膜缺损合并白内障、角膜白斑等)。发现患者85人,患病率5.25/万,14岁以下患者占76.47％。患者亲属患病率0.40％。病因假设为多基因遗传病,经计算遗传度57.04％。环境因素中营养不良比较突出,可能与发病有密切关系。此病波及予东、皖西十余县,约900多万人口地区。按本组患病率估计患者达五千余人,应引起足够重视,深入研究,积极防治。参加单位: 河南中医学院附属医院眼科、河南医学院眼科、周口地区医院眼科、鹿邑县医院眼科及玄武等公社医院、太康县医院眼科及高贤等公社医院、沈邱县医院眼科及连池等公社医院、扶沟县医院眼科及大李庄公社医院等。
From March 5, 1982 to May 10, 1982, a total of 160,000 population in rural areas of Tusi County were surveyed for congenital hypoplasia (including no eyeball, small eyeball, small cornea, cataract with uveal defect, corneal leukoplakia, etc.). 85 patients were found, the prevalence of 5.25 / million, 76.47% of patients under the age of 14. The prevalence of relatives of patients 0.40%. The cause of the hypothesis is polygenic disease, calculated by 57.04% heritability. Malnutrition in environmental factors is more prominent, may be closely related to the incidence. The disease spread to the east, Wanxi more than ten counties, about 9000000 population area. According to the prevalence of this group of patients estimated more than five thousand people, should cause enough attention, in-depth study, and active prevention and treatment. Participants: Department of Ophthalmology, Affiliated Hospital of Henan College of Traditional Chinese Medicine, Department of Ophthalmology, Henan Medical College, Ophthalmology of Zhoukou District Hospital, Luyi County Hospital of Ophthalmology and Xuanwu Commune Hospital, Taikang Hospital of Ophthalmology and Gao Yin and other commune hospitals, Shenqiu Hospital of Ophthalmology and even Pool and other commune hospitals, Fugou County Hospital and Li Zhuang commune hospitals.