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重症感染发病率和病死率较高,抗生素治疗占有不可忽视的地位。随着临床耐药和多重耐药问题的凸显,重症感染的抗生素应用和选择成为临床医师关注的焦点。合理选择和优化应用抗生素是应对耐药菌引起重症感染的有效措施。现重点综述重症感染抗菌治疗的优化策略和个体化用药特点。
The incidence of severe infection and mortality is high, antibiotics occupy a place that can not be ignored. With the clinical drug resistance and multi-drug resistance issues highlighted, the application and selection of antibiotics in severe infections become the focus of clinicians. Rational selection and optimization of antibiotics is to deal with resistant bacteria caused by effective measures to severe infections. Now focuses on the optimization of antimicrobial treatment of severe infections and individualized medication characteristics.