氧是维持人体生命不可缺少的物质,但健康人和动物对氧的耐受性均有一定限度,过多或持久地吸入高浓度或高压氧可影响细胞代谢的化学过程而引起肺、脑等全身脏器的病变,称之为氧中毒。其性质与程度因机体的防御反应,以及暴露于高氧的时间和程度而异。近年来,新生儿重症监护室广泛建立呼吸支持治疗,包括氧疗的应用有很大改进,虽使新生儿,尤其是低出生体重儿的病死率有了大幅度下降,但是临床工作者又面临氧中毒引起肺、眼等病变增多的问题(1)。本文将对新生儿氧中毒引起支气管肺发育不 Oxygen is an indispensable substance to maintain human life, but healthy people and animals have certain limits on oxygen tolerance. Excessive or prolonged inhalation of high concentrations or hyperbaric oxygen can affect the metabolism of cells and cause lung, brain, etc. Whole body organ disease, called oxygen poisoning. Its nature and extent vary with the body’s defensive response and the timing and extent of exposure to hyperoxia. In recent years, extensive support for respiratory support has been established in the neonatal intensive care unit, including oxygen therapy, which has led to significant improvements in the use of oxygen therapy. Despite significant reductions in mortality among newborns, especially those with low birth weights, clinicians are faced with Oxygen poisoning causes lung, eye and other lesions increased (1). This article will cause neonatal oxygen poisoning bronchopulmonary development is not