患者男性，29岁，农场工人。因被大咬伤于1992年8月28日到场医院注射武汉生物制品研究所生产的人用狂犬病疫苗．4小时后，注射部位出现硬结、红肿、疼痛，后改用深圳卫武光明生物制品厂生产的狂犬病疫苗。注射后又出现上述反应，未做任何处理，继续注射至第3针，上述症状急剧加 Male patient, 29 years old, farm worker. Because of a large bite in August 28, 1992 the scene of the hospital injection of rabbits vaccines produced by Wuhan Institute of Biological Products. Four hours later, the site of injection appeared induration, redness, pain, then switch to rabies vaccine produced by Shenzhen Wei Wuming Biological Products Factory. After the injection of the above reaction, without any treatment, continue injection to the third needle, the sharp increase in the above symptoms