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目的探讨分析上消化道出血应用泮托拉唑联合凝血酶的治疗效果。方法 60例上消化道出血患者,随机分为对照组与研究组,每组30例。对照组给予泮托拉唑治疗,研究组在对照组治疗的基础上给予凝血酶治疗。对两组患者的治疗效果进行观察比较。结果研究组治疗总有效率为93.3%,高于对照组的73.3%,差异具有统计学意义(P<0.05);研究组平均输血量为(1.5±0.3)ml、住院时间为(6.3±1.4)d均明显少于对照组的(2.4±0.8)ml、(8.5±2.4)d,差异均具有统计学意义(P<0.05)。结论在上消化道出血的临床治疗中,采用泮托拉唑与凝血酶联合治疗的方式,可以显著提高治疗效果,减少平均输血量,缩短住院时间,是一种值得临床选用与普及的治疗方式。
Objective To investigate the application of pantoprazole combined with thrombin in the treatment of upper gastrointestinal bleeding. Methods Sixty patients with upper gastrointestinal bleeding were randomly divided into control group and study group, 30 cases in each group. The control group was given pantoprazole, and the study group was given thrombin treatment on the basis of the control group. The treatment effect of two groups of patients were observed and compared. Results The total effective rate of the study group was 93.3%, which was higher than that of the control group (73.3%), the difference was statistically significant (P <0.05). The mean blood transfusion volume was (1.5 ± 0.3) ml and the hospitalization time was 6.3 ± 1.4 ) d were significantly lower than those in the control group (2.4 ± 0.8) ml and (8.5 ± 2.4) d, respectively, with statistical significance (P <0.05). Conclusions In the clinical treatment of upper gastrointestinal bleeding, the combination of pantoprazole and thrombin can significantly improve the therapeutic effect, reduce the average blood transfusion and shorten the hospital stay, which is a clinical choice and universal treatment .