利用激光技术治疗开角型青光眼已有近10年的历史。1973年Krasnov首创用Q开关激光作小梁刺孔术(Trabecular laser puncture)。产生刺孔效应的激光,光斑较大或能量较高。在观察随访中,发现其洞口开放时间短、疤痕形成多,疗效可疑。其中38%病例在3～5年内仍需手术控制眼压,而其余62%的病例也需每6个月重复激光一次。Ticho观察的28例患者中,13例需手术,11例需重复激光。此外,在实验动物中尚可产生青光眼。1974年Worthen等人采用低能量、短曝光的氩激光作单一象限的治疗,结果成功率也较低。1979年Wise首次报导使用低能量的氩激光作360°范围内的小梁成形术(Trabeculoplasty或称小梁退缩术Trabecular retraction,tightening)在长期观察随访中,其疗效有较为显著的提高。近一年来,Wise技术得到了日益广泛的应用。以下综述近期文献,对此法作一概要 The use of laser technology for treatment of open angle glaucoma has been nearly 10 years of history. In 1973 Krasnov pioneered the use of Q-switched laser trabecular laser puncture. Produce a puncture effect of the laser, the spot larger or higher energy. In the observation follow-up, found that the hole opening time is short, the formation of more scars, the efficacy of suspicious. Thirty-eight of these patients still require intraocular pressure control within 3 to 5 years, while the remaining 62% of cases require repeated laser every 6 months. Of the 28 patients Ticho observed, 13 required surgery and 11 required laser repetition. In addition, glaucoma can still be produced in experimental animals. In 1974, Worthen et al. Used low-energy, short-exposure argon laser as a single quadrant for treatment and the resulting success rate was also lower. In 1979 Wise first reported that the use of low-energy argon laser in 360 ° trabeculectomy (Trabecul retrasty, or trabecular retraction, tightening) in the long-term follow-up, the effect was significantly improved. The past year, Wise technology has been more widely used. The following is a summary of recent literature, a summary of this method