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临床试用大蒜制剂预防和治疗人巨细胞病毒感染取得了明显效果。在此基础上我们应用细胞病变(CPE)抑制试验和空斑抑制试验,对大蒜中的抗人巨细胞病毒成份进行了初步筛选和比较,证实新鲜大蒜中存在多种抗该病毒的有效成份,其中至少包括大蒜新素(二丙烯三硫)和Ajoene类似物。
Clinical trials of garlic preparations have achieved significant results in the prevention and treatment of human cytomegalovirus infection. Based on this, we used the cytopathic effect (CPE) inhibition test and plaque inhibition test to conduct preliminary screening and comparison of the anti-human cytomegalovirus components in garlic, confirming that there are many kinds of active ingredients in the fresh garlic against the virus. Among them are at least allitin (dipropylene trisulfide) and Ajoene analogues.