论文部分内容阅读
目的 :观察急性心肌梗死 (AMI)患者应用重组组织型纤溶酶原激活剂 (rt- PA)进行静脉溶栓治疗疗效。方法 :动态观察 1 5例 AMI患者溶栓后 2 4h内的心电图、血清酶和临床症状的变化以及梗死后并发症发生率。结果 :临床判断 1 5例总再通率为 86 .7%。冠状动脉造影后证实 75 % (3/ 4)的患者梗死相关血管再通。溶栓过程中未见严重出血及其他副作用。结论 :rt- PA用于临床疗效较确切。总量 1 0 0 mg的疗效显著高于 5 0 mg。
Objective: To observe the effect of intravenous thrombolytic therapy using recombinant tissue plasminogen activator (rt-PA) in patients with acute myocardial infarction (AMI). Methods: The changes of electrocardiogram, serum enzymes and clinical symptoms within 24 hours after thrombolysis in 15 AMI patients were dynamically observed. The incidence of complications after infarction was also observed. Results: The total recanalization rate of 15 cases was 86.7%. Coronary angiography confirmed infarct-related revascularization in 75% (3 of 4) of patients. No severe bleeding and other side effects during thrombolysis. Conclusion: rt-PA for more specific clinical efficacy. The total effect of 100 mg was significantly higher than 50 mg.