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1名59岁,有3年丙型肝炎史(无肝衰或其它疾病)的妇女,在应用左旋咪唑治疗(每两周治疗3天,每天口服150mg)后发生了多灶性脑白质病:在第二疗程后发生神经学症状,在后两个疗程中进行性加重.在应用总量达1800mg后停药.病人无发热,昏睡,定向力障碍,精神错乱,短期记忆丧失,强迫性语言障碍,眩晕,臂无力,共济失调步态,无扶持不能行走.血和脑脊液细胞学检查、生化试验、细菌(霉菌)培养正常或阴性.头部磁共振成像(MRI)显示
A 59-year-old woman with a history of hepatitis C for 3 years (without liver failure or other illnesses) developed multifocal leukoencephalopathy after levamisole treatment (three days every two weeks, 150 mg daily) Neurological symptoms occurred after the second course of treatment, with progressive exacerbations in the last two courses, with discontinuation after a total application of 1800 mg, without fever, lethargy, disorientation, confusion, short-term memory loss, obsessive-compulsive disorder Obstacles, dizziness, weakness of the arm, ataxia gait, unsupported walking, blood and cerebrospinal fluid cytology, biochemical tests, and normal (normal) or negative cultures of bacteria (molds). Head Magnetic Resonance Imaging (MRI)