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原发性肝癌(PHC)患者感染了乙型肝炎病毒(HBV),仅产生少量乙型肝炎表面抗原(HBsAg),这是由于恶性细胞中存在病毒复制的缺陷。Hoofnagle等提出,抗乙型肝炎核心抗原的抗体(抗-HBc)与抗乙型肝炎表面抗原的抗体(抗-HBs)或HBsAg相比,它更明确表示HBV的细胞内复制。本文作者报告,在PHC患者中抗-HBc的检
Patients with primary liver cancer (PHC) are infected with Hepatitis B virus (HBV) and produce only a small amount of Hepatitis B surface antigen (HBsAg) due to the presence of viral replication in malignant cells. Hoofnagle et al. Suggest that antibodies against hepatitis B core antigen (anti-HBc) more specifically indicate the intracellular replication of HBV than antibodies against hepatitis B surface antigen (anti-HBs) or HBsAg. The authors report that anti-HBc tests in PHC patients