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硝硫氰胺(Nithiocyaminum,7505)具有良好地杀灭血吸虫作用,已为国内外的研究证实。以往应用硝硫氰胺微粉三日疗法治疗血吸虫病所见神经精神系统与消化系统副反应较多,肝损害率较高,SGPT值升高占29.8%。为了减低毒付反应,1980年9月~1981年4月,我们采用硝硫氰胺新剂型油滴丸一剂疗法作动物实验与临床观察,现报告如下: 实验研究一、材料和方法 1.用体重20克左右小白鼠,以腹壁贴片法感染血吸虫尾蚴40±1条/只,40天后
Nithiocyaminum (7505) has a good killing effect on schistosomiasis, which has been confirmed by domestic and foreign research. In the past, the application of nitrocellulose powder three days treatment of schistosomiasis in the neuropsychiatric system and digestive system more side effects, higher liver damage, SGPT value increased 29.8%. In order to reduce the poisoning reaction, September 1980 ~ April 1981, we use a new type of nitrocytnamine oil drop pill therapy for animal experiments and clinical observations are reported as follows: Experimental study A, materials and methods 1. With body weight of about 20 grams of mice to the abdominal wall method of infection schistosome cercaria 40 ± 1/40 days later