1临床资料患者男,47岁。双前臂及双手和双足部红斑及皲裂伴瘙痒20d。20d前,无明显诱因患者的双前臂、双手背及双足背出现红斑伴瘙痒,并出现腹泻,为稀水样便,5~6次/d,无发热,当地医院以“过敏性皮炎”予每天肌肉注射曲安奈德针50mg,连用2d,同时口服用止泻药物(药物及剂量不详),无效,且原有红斑基础上出现糜烂及渗出,皮损逐渐干燥结痂,呈暗褐色斑片,并肥厚、粗糙、脱屑,伴皲裂。1周前出现全身乏力并精神萎靡。 1 Clinical data Patient male, 47 years old. Double forearm and hands and feet, erythema and chapped with itching 20d. 20d, there is no obvious incentive in patients with double forearms, both hands and feet back with erythema with pruritus, and diarrhea, watery stool, 5 to 6 times / d, no fever, the local hospital to “atopic dermatitis ”Every day intramuscular injection of triamcinolone acetonide needle 50mg, once every 2d, at the same time oral antidiarrheal drugs (drugs and dose unknown), and the original erythema on the erosion and exudation, the skin lesions gradually dry scab was Dark brown patches, and hypertrophy, rough, scaling, with chapped. A week ago, there was generalized fatigue and apathetic.