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目的 :AJCC/ UICC TNM分期公布已 13年 ,国际上已得广泛应用 ,但国内至今未见用引分期文献报道。这种分期也不太严谨 ,未规定淋巴结检查数目和每枚淋巴结切片数。因此 ,研究结直肠癌淋巴结转移 (L NM)数目与预后的关系可弥补其不足。方法 :用自制的病理检查规范检查结直肠癌的淋巴结 ,分期采用AJCC/ U ICC TNM系统 ,同时作 Dukes分期 ,比较两种分期。结果 :76例共查淋巴结 3885枚 ,每例平均 5 1.5 2± 2 3.15枚。 4 3例有 L NM,L NM率为 5 6 .5 8%。N1 和 N2 病例 5年生存率有高度显著差别。L NM≥ 10枚和/或顶端、主干血管旁 L NM病例的预后极差。结论 :AJCC/ UICC TNM分期优于 Dukes分期 ;AJCC/ UICCTNM分期也有不足 ;提出一新的结直肠癌分期
Purpose: The AJCC/UICC TNM has been published in stages for 13 years and has been widely used internationally. However, no domestic introductory period reports have been reported in the country. This staging is also less stringent and does not specify the number of lymph node examinations and the number of lymph node sections. Therefore, to study the relationship between the number of lymph node metastasis (L NM) and prognosis in colorectal cancer can make up for its deficiency. METHODS: Lymph nodes of colorectal cancer were examined with self-made pathological examination criteria. The AJCC/U ICC TNM system was used for staging and the Dukes stage was performed at the same time to compare the two stages. Results: In 76 cases, 3885 lymph nodes were examined, and each case averaged 5 1.5 2±2 3.15 pieces. In 43 patients, L NM and L NM were 5 6 . 5 8%. There was a highly significant difference in 5-year survival rates between N1 and N2 cases. Patients with L NM ≥ 10 and/or apical, main vascular LNM cases had poor prognosis. Conclusion: AJCC/UICC TNM staging is better than Dukes staging; AJCC/UICCTNM staging is also insufficient; a new colorectal cancer staging is proposed