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[目的]了解费县健康人群百日咳、白喉、破伤风抗体水平,评价百白破三联制剂免疫效果,为制定免疫策略提供科学依据。[方法]2008年随机抽取费县446名健康人群进行血清百日咳、白喉、破伤风抗体水平检测。[结果]检测446人,百日咳抗体保护率为68.39%,抗体几何平均滴度为1∶306.56;白喉抗毒素均值为0.11 IU/ml,保护率为77.13%;破伤风抗毒素均值为0.12 IU/ml,保护率为76.01%。百日咳、白喉、破伤风抗体保护率,<15岁组分别为76.53%、84.24%、83.42%。[结论]费县15岁以下健康人群对百日咳、白喉、破伤风均有较高的免疫水平,但15岁以上人群的抗体水平明显降低。
[Objective] To understand the levels of pertussis, diphtheria and tetanus antibodies in healthy population of Feixian County and evaluate the immunization effect of Baibuhe Sanlian Preparation for providing a scientific basis for formulating immunization strategies. [Method] In 2008, 446 healthy people from Fei County were randomly selected for serum pertussis, diphtheria and tetanus antibody test. [Results] The detection rate of tetanus antitoxin was 68.39%, the geometric mean titer of antibody was 1:306.56, the average value of diphtheria antitoxin was 0.11 IU / ml and the protective rate was 77.13%. The average value of tetanus antitoxin was 0.12 IU / ml, The protection rate was 76.01%. Pertussis, diphtheria and tetanus antibody protection rates were 76.53%, 84.24% and 83.42% respectively in the 15-year-old group. [Conclusion] The healthy population below 15 years old in Feixian had a higher level of immunity to whooping cough, diphtheria and tetanus, but the antibody level in people over 15 years old was obviously lower.