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目的 :探讨不同类型抗精子抗体对精子功能的影响。方法 :对 2 30例单一血清抗精子抗体阳性的不育男性采用ELISA方法测定其血清中三种类型抗精子抗体 ,经与精液质量的比较分析并与本中心 2 0 0例正常生育男性的精液质量进行比较分析 ,结果 :抗精子抗体阳性组的精液质量与对照组相比其精子活率、活力下降 ,死亡率、畸形率上升 ,液化时间延长 ,IgM、IgG两类抗体对精子的质量影响尤其显著。结论 :IgG、IgA、IgM三类抗精子抗体都会降低生育力 ,IgG、IgM的影响最为明显
Objective: To investigate the effect of different types of anti-sperm antibodies on sperm function. Methods: Two hundred and seventy male infertile men with single serum anti-sperm antibody were tested for serum anti-sperm antibodies in three types of sera by sperm quality comparison analysis and with the center of 200 normal fertility male sperm The results showed that compared with the control group, the sperm motility, motility, mortality, deformity rate and liquefaction time of semen in the anti-sperm antibody positive group were significantly higher than those in the control group Especially notable. Conclusion: Anti-sperm IgG, IgA, IgM antibodies can reduce fertility, the most obvious impact of IgG, IgM