该研究检测了慢性血小板减少性紫癜(TP)治疗中血小板和血浆中的抗血小板自身抗体(AAb)。方法有明确免疫性血小板减少症(血小板≤150×10~9/L),病程在6个月以上的儿童(67例)和成人(23例)即诊断为慢性 TP,患者伴随疾病有系统性红斑狼疮5例,慢性淋巴细胞性白血病1例,人类免疫缺陷病毒感染1例,肉瘤1例,新生儿 TP1例,12例因标本含血小板不足(<10~8)被除外。患者至少3 This study examined antiplatelet autoantibodies (AAb) in platelets and plasma in the treatment of chronic thrombocytopenic purpura (TP). Methods: A clear diagnosis of immune thrombocytopenia (platelet ≤ 150 × 10 ~ 9 / L), duration of 6 months or more in children (67 cases) and adults (23 cases) that is diagnosed as chronic TP, patients with systemic disease 5 cases of lupus erythematosus, 1 case of chronic lymphocytic leukemia, 1 case of human immunodeficiency virus infection, 1 case of sarcoma, 1 case of newborn and 12 cases of platelet deficiency (<10 ~ 8). Patient at least 3