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目的探讨垂体后叶素联合酚妥拉明治疗肝硬化上消化道出血的临床疗效。方法对82例出血患者采用垂体后叶素+酚妥拉明(治疗组)和单纯垂体后叶素(对照组)治疗,比较两组止血效果和并发症情况。结果治疗组、对照组在止血效果方面差异无统计学意义(P>0.05),但并发症发生率差异有统计学意义(P<0.01)。结论在用垂体后叶素止血的同时,运用酚妥拉明,可减轻垂体后叶素带来的副作用,扩大垂体后叶素的使用范围及剂量。
Objective To investigate the clinical efficacy of pituitrin combined with phentolamine in the treatment of upper gastrointestinal bleeding in cirrhosis. Methods Eighty patients with hemorrhage were treated with pituitrin + phentolamine (treatment group) and pituitrin alone (control group). The hemostatic effects and complications of the two groups were compared. Results There was no significant difference in the hemostatic effects between the treatment group and the control group (P> 0.05). However, the incidence of complications was statistically significant (P <0.01). Conclusions In the use of pituitrin hemostasis at the same time, the use of phentolamine, pituitrin can reduce the side effects caused by vasopressin to expand the scope and dose.