目的:评估临床药师实施干预措施对降低苯二氮类药用量的效果。方法:临床药师为重复应用苯二氮类药3个月以上的成年患者制订撤药方案,以每2周减量10%的梯度法减量,并予以单盲撤药。结果:临床药师实施干预措施后,苯二氮类药用量明显下降,平均下降率为70.50%。结论:临床药师在苯二氮类药撤药过程中起了关键作用,其干预措施是帮助医师降低患者苯二氮类药用量的快速、有效方法。 PURPOSE: To assess the effect of clinical pharmacist interventions on reducing benzodiazepine use. Methods: The clinical pharmacist developed an abstinence regimen for adult patients who had been repeatedly treated with benzodiazepines for more than 3 months. The drug was reduced by a gradient method of 10% every 2 weeks and was withdrawn by single blind. Results: After the clinical pharmacist implemented interventions, the dosage of benzodiazepines dropped obviously with the average rate of decrease being 70.50%. CONCLUSIONS: Clinical pharmacists play a key role in the withdrawal of benzodiazepines, and their interventions are a fast and effective way to help physicians reduce the amount of benzodiazepines in patients.