目的:探讨口服铁剂改善孕期贫血及铁储备状态的作用。方法:选择144例妊娠贫血孕妇(贫血组,口服多糖铁复合物胶囊150 mg/次,2次/天)、100例正常孕妇(预防组,口服多糖铁复合物胶囊150 mg/次,1次/天)和50例正常孕妇(对照组,膳食补铁),测定血红蛋白(Hb)、红细胞计数(RBC)、血清铁蛋白(SF)、血清铁(SI)。结果:贫血组和预防组Hb和RBC呈现早-中期下降(P<0.05)、中-晚期上升(P<0.05)的变化,对照组各孕周Hb、RBC呈逐渐下降趋势(P<0.05)。整个孕周3组孕妇SF均呈进行性下降(P<0.01)。3组孕妇SI早-中期下降较为明显(P<0.01)。结论:单纯膳食补铁不能满足孕期对铁的需求。孕期铁储备处于持续消耗状态。需重视孕早期及孕中期铁剂补充。 Objective: To investigate the role of oral iron in improving anemia during pregnancy and the state of iron reserve. Methods: One hundred and seventy pregnant women with anemia of pregnancy (anemia group, oral polysaccharide compound 150 mg / time, twice daily) and 100 normal pregnant women (preventive group, oral polysaccharide iron complex 150 mg / time, Day) and 50 normal pregnant women (control group, dietary iron supplementation). Hb, RBC, SF and SI were measured. Results: The levels of Hb and RBC in the anemia group and the prophylaxis group were decreased in the early-middle stage (P <0.05) and in the mid-late stage (P <0.05), while the levels of Hb and RBC in the control group were gradually decreased (P <0.05) . The SF of the three pregnant women in the three gestational weeks decreased progressively (P <0.01). The early to mid-term declines of SI group were more obvious (P <0.01). Conclusions: Dietary iron alone can not meet the demand for iron during pregnancy. Pregnancy iron reserves in a state of sustained consumption. Should pay attention to early pregnancy and second trimester iron supplementation.