龋病是影响人们健康最常见的口腔疾病。据石四箴报道,儿童1岁即可发生龋病,以后迅猛增加,至7～9岁发病率可高达80%以上。细菌因素是龋病发生的关键,目前公认变形链球菌(变链菌)是重要的致龋菌。已有资料报道,厚朴的主要成分,厚朴酚及和厚朴酚对变链菌有高效快速杀菌作用。因此推测厚朴将有可能成为防龋药物之一。 Dental caries is the most common oral disease affecting people's health. According to Shi-Zhen reported that children can occur at the age of 1 caries, after the rapid increase, to 7 to 9-year-old incidence can be as high as 80%. Bacterial factors is the key to caries, Streptococcus mutans (Streptococcus mutans) is recognized as an important cariogenic bacteria. It has been reported that the main components of Magnolia officinalis, honokiol and honokiol Streptococcus mutans have efficient and rapid bactericidal effect. Therefore speculated that Magnolia will be one of the anti-caries drugs.