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目的:探讨经皮乙醇注射对原发性肝癌患者细胞免疫功能的影响。方法:对24例肝癌患者进行经皮乙醇注射治疗,观察治疗前、后外周血CD4、CD8淋巴细胞的变化。结果:治疗后4,8周CD4、CD4/CD8明显高于治疗前及对照组(P<0.05),且术中无并发症发生。结论:经皮乙醇注射注射可以改善原发性肝癌患者细胞免疫功能,是治疗原发性肝癌安全、有效的手段之一,但其长期疗效和对细胞免疫的影响有待于进一步研究。
Objective: To investigate the effects of percutaneous ethanol injection on cellular immune function in patients with primary liver cancer. Methods: Twenty-four patients with HCC were treated with percutaneous ethanol injection to observe the changes of CD4 and CD8 lymphocytes in peripheral blood before and after treatment. Results: CD4 and CD4 / CD8 levels at 4 and 8 weeks after treatment were significantly higher than those before and after treatment (P <0.05), and no intraoperative complications occurred. Conclusion: Percutaneous ethanol injection can improve cellular immune function in patients with primary liver cancer, which is one of the safe and effective methods for the treatment of primary liver cancer. However, its long-term efficacy and its effect on cellular immunity need to be further studied.