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目的比较等效镇痛剂量的舒芬太尼和芬太尼联合丙泊酚用于无痛人工流产的麻醉效果及安全性。方法选择ASAⅠ-Ⅱ级,无人流禁忌证及药物变态反应史的孕妇100例,随机分为两组(A、B),每组50例。A组麻醉用药为:芬太尼+丙泊酚;B组麻醉用药为舒芬太尼+丙泊酚。观察两组用药后麻醉效果及平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SPO2)的变化。结果两组麻醉效果、诱导时间、清醒时间、自行离院时间及丙泊酚总量对呼吸、循环的影响等方面均差异有统计学意义(P<0.05),B组效果较好。结论舒芬太尼复合丙泊酚用于无痛人工流产的麻醉效果优于芬太尼联合丙泊酚,不但呼吸和循环稳定,而且能有效的抑制患者术后的宫缩痛从而提高患者的满意率。
Objective To compare the efficacy and safety of sufentanil with fentanyl and propofol in analgesic induced abortion. Methods One hundred pregnant women with history of ASA Ⅰ-Ⅱ, no contraindications of abortion and history of drug allergy were randomly divided into two groups (A and B), 50 cases in each group. A group of anesthesia medication: fentanyl + propofol; B group anesthesia for sufentanil + propofol. The anesthetic effects and mean arterial pressure (MAP), heart rate (HR) and pulse oxygen saturation (SPO2) were observed after treatment. Results There were significant differences in the effects of anesthesia, induction time, awake time, time spent on leaving hospital and the total amount of propofol on respiration and circulation in both groups (P <0.05). The effect in group B was better. Conclusion Sufentanil combined propofol is more effective than fentanyl combined with propofol in painless induced abortion. It not only has stable respiratory and circulatory functions, but also can effectively inhibit uterine contractions in patients with postoperative pain Satisfaction rate.