观察69例,均经肝活捡或死后肝穿、尸检证实,属轻型者24例,中型28例,重型28例。入院时病程分别为13.6±7.0天、29.2±30.3天、41.8±44.2天,病程愈短,肝坏死程度愈轻。症状体征及肝功能指标的变化,合并症的多少,病死率的高低等均与病期轻重相一致,认为病理分期是可行的,对早期诊断提出如下要点:全身中毒症状超过3周不能 Sixty-nine cases were observed by liver biopsy or post-mortem liver biopsy, which were confirmed by autopsy. There were 24 cases with mild type, 28 with medium type and 28 with heavy type. Duration of admission were 13.6 ± 7.0 days, 29.2 ± 30.3 days, 41.8 ± 44.2 days, the shorter the duration of the disease, the less the degree of liver necrosis. Symptoms and signs and changes in liver function indicators, the number of complications, the level of mortality are consistent with the severity of disease that the pathological staging is feasible, the following points made on the early diagnosis: symptoms of systemic poisoning can not be more than 3 weeks