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目的 :了解血透患者中丙型肝炎病毒的感染情况 ,并探讨相关的危险因素。方法 :对 15 0例维持性血透患者应用逆转录聚合酶链反应及酶联免疫吸附法检测血清中HCV -RNA及抗HCV -IgG的水平。结果 :HCV -RNA的阳性率为 2 6 7% (4 0 / 15 0例 ) ;抗HCV -IgG的阳性率为 2 4% (36 / 15 0例 ) ;HCV感染率 (总阳性率 )为 35 3 %(5 2 / 15 0例 )。结论 :提示血透患者中HCV感染率明显高于普通人群。输血及血制品是其第一位的危险因素 ,而透析器及管路的交叉使用也是不容忽视的危险因素之一
Objective: To understand the infection of Hepatitis C virus in hemodialysis patients and explore the related risk factors. Methods: Serum HCV-RNA and anti-HCV-IgG levels were measured by reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay in 150 patients with maintenance hemodialysis. Results: The positive rate of HCV-RNA was 26.7% (40/1050). The positive rate of anti-HCV-IgG was 24% (36/1500). The positive rate of HCV infection was 35 3% (5 2/15 0 cases). Conclusion: It is suggested that the infection rate of HCV in hemodialysis patients is obviously higher than that in the general population. Blood transfusion and blood products are the first risk factors, and dialyzer and pipeline cross-use is also one of the risk factors can not be ignored