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本文报告80名HBsAg阳性母亲所生婴儿的HBV感染的10年观察结果。80名婴儿在6个月时HBsAg阳性率为51.34％,HBV感染率为52.5％,75％婴儿呈HBsAg持续携带状态。出生后6个月时HBsAg阴性的婴儿至10年时HBsAg阳性率为19.3％,HBV感染率为46.7％,80名婴儿在10年中HBsAg累积阳性率为65.1％,HBV总感染率为77.7％,表明HBsAg阳性母亲的婴儿除母婴传播外,水平传播也不容忽视,强调对HBsAg阳性母亲的新生儿及乙肝高发区普遍对新生儿进行预防免疫的重要性。
This article reports the 10-year observation of HBV infection in 80 infants born to HBsAg-positive mothers. The positive rate of HBsAg in 80 infants was 51.34% at 6 months, the rate of HBV infection was 52.5%, and 75% of infants showed HBsAg sustained status. At 6 months after birth, HBsAg-negative infants at the age of 10 had a HBsAg positive rate of 19.3% and HBV infection rate of 46.7% at 10 months. The positive rate of HBsAg accumulation in 80 infants was 65.1% at 10 years and the total HBV infection rate was 77.7% , Indicating that in addition to mother-to-child transmission of HBsAg-positive mothers, the level of transmission should not be overlooked, emphasizing the importance of immunization against newborns in HBsAg-positive mothers and hepatitis B-prone areas.