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目的观察评价射频消融(REA)治疗肺部肿瘤远期疗效。方法 86例肺癌患者,行CT介导下射频消融治疗,随访评价疗效。结果打开电极至退针平均时间(38.4±10.3)min,REA后行CT见病灶阴影增大、体积增大,CT值下降,术中无相关并发症;术后数日,并发16例次,其中气胸15例次,未见死亡;术后1个月复查,病灶大小无显著变化,SPECT测病灶T/N值恢复至正常水平;术后3个月复查,无死亡例,病灶消失或缩小1 cm左右;随访时间6~24个月不等,7例行二次REA,消融时间距首次REA 6~12个月不等;至2013年12月,死亡19例,距首次REA治疗3~15个月不等,最短98 d,最长487 d,平均(7.1±2.9)个月;1年内生存76例,生存率88.37%。结论射频消融是一种治疗肺部肿瘤可行方法 ,安全可靠,通过破坏肿瘤细胞形态与结构,抑制原发或转移病灶增殖,有助于延长患者生存期。
Objective To evaluate the long-term efficacy of radiofrequency ablation (REA) in the treatment of lung cancer. Methods A total of 86 patients with lung cancer underwent radiofrequency catheter ablation under CT scan. The follow-up evaluation was made. Results The average time from opening the electrode to withdrawing the needle was 38.4 ± 10.3 min. After the REA, the shadow of the lesion increased, the volume increased, the CT value decreased, and no complications were found during the operation. A few days after the operation, 16 cases were followed up, There were 15 cases of pneumothorax without any death. One month after the operation, there was no significant change in the size of the lesion. The T / N value of the SPECT lesion returned to normal level. No recurrence was found at 3 months after operation. The lesion disappeared or disappeared 1 cm; follow-up time ranging from 6 to 24 months, 7 cases of secondary REA, ablation time from the first REA ranging from 6 to 12 months; to December 2013, 19 patients died, from the first REA treatment of 3 ~ 15 months, the shortest 98 d, the longest 487 d, an average of (7.1 ± 2.9) months; 76 cases of survival within 1 year, the survival rate of 88.37%. Conclusion Radiofrequency ablation is a feasible method for the treatment of lung cancer. It is safe and reliable. It can inhibit the proliferation of primary or metastatic lesions by destroying the morphology and structure of tumor cells and prolong the survival of patients.