本文旨在以评价的观点对日常临床合理选用抗生素予以介绍。其中主要是讨论抗生素,但也涉及狭义的化学治疗药,如增效磺胺甲基异(口恶)唑。在得到病原体证实和药敏试验报告之前所采取的初期治疗,即所谓“推测”治疗,是抗生素治疗中最困难的一步。这必须以当时病情中病原体出现的增殖、耐药情况以及机 This article aims to evaluate the point of view of routine clinical rational use of antibiotics to be introduced. Among these are antibiotics, but also narrowly defined chemotherapeutic drugs such as synergistic sulfamethoxazole. The initial treatment taken prior to reporting pathogens and drug susceptibility testing, the so-called “guess”, is one of the most difficult steps in antibiotic therapy. This must be based on the prevalence of pathogen emergence of proliferation, drug resistance and machine