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通常认为,作为全身性疾病之一,外科治疗对非何杰金淋巴瘤的作用不大,因其作用限于局部。手术仅为病检提供所需组织。放疗和化疗则有较好疗效。因手术切除加放疗用于病变限于腺体的甲状腺非何杰金淋巴瘤(NHLT)效果良好,有局部浸润或淋巴结转移致病变不能完全切除者,是否采取手术切除瘤块加放疗或仅限于取活组织加辅助治疗,人们有不同意见。为了解手术对NHLT的术前分期、能达到满意效果所需切除范围及治疗失败情况,作者分析美国Mayo临床医院1965～1989确诊后6个月之内初治使用切除方法的原发NHLT62例,仅行切除者6例,切除加放疗42例,切除加化疗10例,合用切除、放疗和化疗4例。50例术后分期属ⅠE或ⅡE期,余为ⅢE和ⅣE期。全组5年和10年总生存率各为53%和46%。ⅠE期病变限于
Surgical treatment is generally considered to have little effect on non-Hodgkin’s lymphoma as one of the systemic diseases because its effect is limited to local. Surgery only provides the required tissue for medical examinations. Radiotherapy and chemotherapy have a good effect. Nerve Thyroid Non-Hodgkin Lymphoma (NHLT) with lesions confined to the gland for surgical resection plus radiotherapy is effective, local infiltration or lymph node metastasis can not be completely resected, whether surgical resection of the tumor plus radiotherapy or only Taking live tissue and adjuvant therapy, people have different opinions. To understand the preoperative staging of the NHLT, the range of resection required to achieve satisfactory results, and the treatment failure, the authors analyzed 62 cases of primary NHLT that were initially treated within 6 months after diagnosis at Mayo Clinical Hospital in the United States from 1965 to 1989. Only 6 cases underwent resection, 42 cases underwent resection and radiotherapy, 10 cases underwent resection and chemotherapy, and 4 cases underwent combined resection, radiotherapy and chemotherapy. The postoperative stage of 50 cases was IE or IIE, and the remainder was IIIE and IVE. The overall 5-year and 10-year overall survival rates for the whole group were 53% and 46%. IE stage lesions are limited