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岩黄连为罂粟科紫堇属植物Corydalis SaxiCola Bunting的全草,对疮疥肿毒及肝炎。有一定的疗效。为了寻找有效成分,我们提取了总生物碱并进一步分离,共得到12个结晶单体,在强碱性部位分离得到一黄色结晶单体,经物理常数测定,红外光谱,紫外光谱、核磁共振波谱等鉴定为卡维丁(Cavidine)的脱氢对映体,名为脱氢卡维丁(dehydrocavidine),其药理作用的研究情况已有报导,本文介绍其抗菌作用的实验简况。
Rhizoma Coptidis is a whole plant of Papaveraceae Corydalis SaxiCola Bunting, and it has swollen boils and hepatitis. Has a certain effect. In order to find effective ingredients, we extracted total alkaloids and further separated them, and obtained a total of 12 crystalline monomers, which were isolated at a strongly basic site to obtain a yellow crystalline monomer, determined by physical constants, infrared spectra, ultraviolet spectra, and nuclear magnetic resonance spectra. It was identified as the dehydro-enantiomeric enantiomer of Cavidine, named dehydrocavidine, and its pharmacological effects have been reported. This article describes the experimental profile of its antibacterial activity.