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对儿童支气管哮喘的治疗迄今尚不够满意,远期效果更不理想。发病时常选用β_2受体兴奋剂,它对症疗效好,但预防作用不理想。为了减轻患者发作时的痛苦,理想的控制症状药物应能防止肥大细胞脱颗粒,抑制活性介质释放,从而阻断引起支气管平滑肌痉挛的环节。色甘酸钠虽有保护肥大细胞膜的作用,但因其给药途径的限制及药物颗粒本身的刺激性患儿使用不便。当今仍切希望有一种既有膜保护功能、抑制介质释放,又可口服,且易被患者接受的药物。中药黄芩、丹皮、桂枝及甘草具有抗过敏及抑制肥大细胞脱颗粒的作
The treatment of children with bronchial asthma has so far not been satisfactory, the long-term effect is more unsatisfactory. Β 2 receptor agonist often used in the pathogenesis, it is symptomatic effective, but the preventive effect is not ideal. In order to reduce the pain of patients with seizures, the ideal control of symptoms should prevent degranulation of mast cells and inhibit the release of active mediators, thus blocking the spasm that causes bronchial smooth muscle. Although cromolyn sodium mantle cell membrane to protect the role, but because of its route of administration and drug particles themselves irritation of children with inconvenience. Today there is still a desire for a drug that has both membrane protection, media release inhibition, orality, and patient acceptance. Traditional Chinese medicine skullcap, paeonol, cassia twig and licorice with anti-allergic and inhibit mast cell degranulation