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50例原发性高血压病人,其中高血浆肾素12例(均为男性,平均年龄41.8±3.2岁),正常血浆肾素31例(男性24例,女性7例,平均47.5±2.2岁),低血浆肾素7例(男2例,女5例,平均年龄56.1±3.7岁)。口服心得安 80～160mg/日,3周后分析心得安对肾素及醛固酮的作用。服心得安后,病人的血压有显著降低,在高肾素组平均血压降低最明显,正常肾素组次之,低肾素组最少。除低肾素组的舒张压有轻度增加外,其余2组均下降,舒张压增加的程度与治疗前血浆肾素值呈负相关(γ=-0.79,P <0.05),即血浆肾素值愈低者舒张压增加愈明显。可能因这些病人中,心得安
50 patients with essential hypertension, including 12 cases of high plasma renin (both men, mean age 41.8 ± 3.2 years), normal plasma renin 31 cases (24 males and 7 females, mean 47.5 ± 2.2 years) , 7 cases of low plasma renin (2 males and 5 females, mean age 56.1 ± 3.7 years). An oral experience An 80 ~ 160mg / day, 3 weeks after the analysis of Proenin and aldosterone. Serve peace of mind, the patient’s blood pressure was significantly lower in the high renin group, the average blood pressure was the most obvious, followed by the normal renin group, the lowest renin group. Except diastolic pressure in the low renin group increased slightly, the other two groups decreased, and the degree of increase in diastolic pressure was negatively correlated with the plasma renin before treatment (γ = -0.79, P <0.05), that is, plasma renin The lower the value of the more obvious increase in diastolic blood pressure. Perhaps because of these patients, peace of mind