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由于假阴性和假阳性反应,血吸虫粗抗原皮内试验近年来已不为人所喜用。为了提高血吸虫皮内试验抗原的可靠性,作者提纯了一种血吸虫酸性蛋白水解酶,能致敏宿主,只引起速发型超敏反应,对埃及或曼氏血吸虫感染均有特异性。作者用小鼠肥大细胞脱粒试验及猴皮内试验对曼氏及埃及血吸虫粗抗原与提纯蛋白水解酶的抗原性质进行了比
Due to false-negative and false-positive reactions, schistosome crude antigen intradermal test in recent years has not been used by people. In order to improve the reliability of anti-schistosoma antigens tested in skin, the authors purified a schistosome acidic proteolytic enzyme that sensitized the host, causing only immediate hypersensitivity reactions, and specificity for either Schistosoma mansoni or Schistosoma mansoni infection. The authors used mouse mast cell degranulation test and the monkey skin test to compare the antigenic properties of Mann and Schistosoma japonicum crude antigen and purified proteolytic enzymes