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本文检测了80例丙型肝炎(HC)和30例丙型肝炎相关肝细胞癌(HCRHCC)的甲胎蛋白(AFP)和碱性磷酸酶(ALP)水平。AFP的水平在慢性迁延性丙型肝炎、中型慢性活动性丙型肝炎、重型慢性活动性丙型肝炎、丙型肝炎后肝硬化和HCRHCC各组之间存在差异。AFP和ALP在不同分化程度的HCRHCC中的差异无显著性。结果提示,AFP不仅可作为协助HCRHCC诊断的指标,而且,根据临床资料推测HC的病理分型,AFP的水平可作为一项比较灵敏的参考指标。未发现AFP和ALP的水平能反映HCRHCC的分化程度。
This article tested the levels of AFP and ALP in 80 patients with hepatitis C (HC) and 30 patients with hepatitis C-associated hepatocellular carcinoma (HCRHCC). AFP levels differ between groups of chronic persistent hepatitis C, chronic active hepatitis C of moderate form, chronic active hepatitis C of severe form, posthepatitis C cirrhosis and HCRHCC. The difference of AFP and ALP in HCRHCC with different degree of differentiation was insignificant. The results suggest that AFP can not only be used as an index to assist in the diagnosis of HCRHCC, but also based on clinical data speculated that the pathological type of HC, AFP levels can be used as a more sensitive reference index. The level of AFP and ALP was not found to reflect the degree of differentiation of HCRHCC.