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胰岛素生长因子 - 1 (IGF - 1 )是一个氨基酸序列与胰岛素相似的多肽。是由垂体分泌的生长激素 (GH)作用于肝脏等外周组织和器官合成并分泌的。循环中的IGF - 1与其结合蛋白结合 (IGFBP - 3)结合 ,呈结合状态。IGF - 1是许多细胞系重要的有丝分裂原 ,具有促进细胞分裂、增殖、
Insulin growth factor - 1 (IGF - 1) is a polypeptide whose amino acid sequence is similar to that of insulin. Is a growth hormone (GH) secreted by the pituitary that acts on the synthesis and secretion of peripheral tissues and organs such as the liver. The circulating IGF - 1 binds to its binding protein (IGFBP - 3) and is bound. IGF-1 is an important mitogen for many cell lines and has the potential to promote cell division, proliferation,