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交感神经系统通过其β—肾上腺素能作用,加速心率和增强心肌收缩力而显著地影响心肌耗氧量。应用具有阻断交感作用的β—肾上腺素能阻滞剂,是心绞痛症状治疗的一大进展。心得安不具有内源性拟交感活性。心得静是具有显著内源性拟交感活性的一种新β—受体阻滞药,内源性拟交感活性在治疗中对心脏的利弊尚有争论。本文旨在比较这两种药物在心绞痛病人中的临床疗效。方法:经冠状动脉造影证实或心肌梗塞后三个月确诊为冠心病心绞痛者41例(男35例,女6例,平均55岁),心绞痛至少近三个月来每二周中发作5
The sympathetic nervous system significantly affects myocardial oxygen consumption through its β-adrenergic action, acceleration of heart rate and enhancement of myocardial contractility. The use of β-adrenergic blockers with sympathetic blockade is a major advance in the treatment of angina. An Ann does not have endogenous sympathomimetic activity. Calm stillness is a new β-blocker with significant endogenous sympathomimetic activity, and the pros and cons of the heart in the treatment of endogenous sympathomimetic activity is still debated. This article aims to compare the clinical efficacy of these two drugs in patients with angina. METHODS: Forty-one patients (35 males and 6 females, mean age 55 years) with confirmed coronary angina pectoris at three months after coronary angiography were confirmed by coronary angiography or angina pectoris were attacked every two weeks for at least three months