早在19世纪末期,德国的病理学家(Bitch-Hirschfeld,1882;Siegerf,1893)就指出,肺癌是支气管源性肿瘤,是源于支气管粘膜上皮,粘膜下腺体和肺泡上皮。近几十年来,随着电镜及组织化学方法的广泛应用,人们对肺癌组织发生的研究日益深入。由于研究方法不同,研究结果各异,因而对肺癌的组织发生仍存在许多分歧。本文仅就这方面的研究进展简介如下。 As early as the late 19th century, the German pathologist (Bitch-Hirschfeld, 1882; Siegerf, 1893) pointed out that lung cancer is bronchogenic cancer, is derived from bronchial epithelium, submucosal glands and alveolar epithelium. In recent decades, with the wide application of electron microscopy and histochemical methods, the research on the occurrence of lung cancer has become more and more in-depth. Because of different research methods and different research results, there are still many differences in the occurrence of lung cancer. This article only summarizes the research progress in this area as follows.