目的研究拉米夫定联合复方甘草酸苷治疗慢性乙型肝炎的临床疗效。方法用拉米夫定联合复方甘草酸苷治疗慢性乙型肝炎52例,观察治疗前后肝功能各项指标变化。结果拉米夫定联合复方甘草酸苷治疗后血清ALT、AST、GGT、TBiL较治疗前明显下降。结论拉米夫定联合复方甘草酸苷治疗慢性乙型肝炎是有效和安全的。 Objective To study the clinical efficacy of lamivudine combined with compound glycyrrhizin in the treatment of chronic hepatitis B. Methods 52 patients with chronic hepatitis B were treated with lamivudine combined with compound glycyrrhizin. The indexes of liver function before and after treatment were observed. Results The serum levels of ALT, AST, GGT and TBiL after lamivudine combined with compound glycyrrhizin were significantly lower than those before treatment. Conclusion Lamivudine combined with compound glycyrrhizin in the treatment of chronic hepatitis B is effective and safe.