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目的 观察中西医结合方法治疗重症溃疡性结肠炎的临床疗效。方法 选择 6 0例重症溃疡性结肠炎患者 ,急性发作期以水杨酸和皮质激素治疗为主 ,配合内服中药和苦参槐花合剂保留灌肠 ,缓解期以口服健脾灵为主 ,辅以水杨酸制剂维持治疗半年以上 ,观察其临床疗效和远期随访结果。结果 内科保守治疗 5 5例 ,完全缓解 35例 (6 3 6 % ) ,有效 18例 (32 7% ) ,无效及死亡各 1例 (1 8% )。中转手术治疗 5例(8 3% ) ,完全缓解 4例 ,有效 1例。远期随访 4 3例 ,远期完全缓解率 6 7 4 % ,癌变率 2 3% ,死亡率 4 7% ,手术率 6 9%。结论 中西医结合治疗重症溃疡性结肠炎临床疗效优于单纯西医疗法 ,能明显降低死亡率和手术率。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of severe ulcerative colitis. Methods Sixty patients with severe ulcerative colitis were selected. Salicylic acid and corticosteroids were mainly used in the acute exacerbation period. Internal medicine and Sophora alopecuroides mixture were used to preserve the enema. In the remission period, oral Jianpi Ling was the main supplement and supplemented by Salicylic acid preparations for more than six months to maintain treatment, observe the clinical efficacy and long-term follow-up results. Results The conservative treatment of internal medicine in 55 cases, complete remission in 35 cases (63.6%), effective in 18 cases (32.7%), ineffective and death in 1 case (18%). Transurethral surgery in 5 cases (83%), complete remission in 4 cases, effective in 1 case. Long-term follow-up 43 cases, long-term complete remission rate of 67.4%, cancer rate of 23%, mortality rate of 47%, operation rate of 69%. Conclusion The clinical curative effect of integrated traditional Chinese and western medicine in the treatment of severe ulcerative colitis is better than that of western medicine alone, which can significantly reduce the mortality and operation rate.