论文部分内容阅读
本文用鼠抗人胃癌单克隆抗体(MG系列)免疫酶法对结肠癌、良性肠道疾病患者及正常人血清中 MG-Ags 的表达进行检测,并观察进展期结肠癌患者手术前后血清中MG-Ags的变化。以探讨 MG-Ags检测的临床意义。以 48例正常人血清 MG-Ags检测 OD值的均数加 3个标准差之和作为判断肿瘤的阳性阈值,结肠癌阳性率为70％(14/20),良性疾病为8％(2/25),48例正常人假阳性为2.1％,结肠癌切除后血清中 MG-Ags水平明显降低。结果证实,MG-Ags检测对进展期结肠癌患者的血清诊断及术后随访具有重要意义。
The expression of MG-Ags in serum of patients with colon cancer, benign bowel disease and normal people was detected using mouse anti-human gastric cancer monoclonal antibody (MG series) immunoenzymatic method, and the serum MG levels in patients with advanced colon cancer before and after surgery were observed. - Changes in Ags. To explore the clinical significance of MG-Ags detection. The median OD value of MG-Ags detected in 48 normal subjects plus the sum of 3 standard deviations was used as a positive threshold for judging tumors. The positive rate of colon cancer was 70% (14/20), and benign disease was 8% (2/ 25) False positives were found in 2.8% of 48 normal subjects. The serum levels of MG-Ags were significantly reduced after resection of colon cancer. The results confirmed that MG-Ags detection is of great significance for the diagnosis and follow-up of patients with advanced colon cancer.