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目的：比较脑神经生长素（ＣＮＧ）与胞磷胆碱（Ｃｉｔ）治疗急性脑出血所致神经功能障碍的疗效。方法：ＣＮＧ组５６例［男性３２例，女性２４例；年龄（６１±ｓ５）ａ］，病程（３．８±１．５）ｄ；出血量（２０．５±２．３）ｍＬ；用ＣＮＧ２～４ｍＬ，ｉｍ，ｑｄ，用药１０～２０ｄ者３０例，２１～３０ｄ者２６例。Ｃｉｔ组６０例［男性３８例，女性２２例；年龄（５９±９）ａ］，病程（３．５±１．７）ｄ；出血量（１９．３±２．８）ｍＬ；Ｃｉｔ５００ｍｇ于５％葡萄糖注射液５００ｍＬ中静脉滴注，ｑｄ，用药１０～２０ｄ者２４例，２１～３０ｄ者３６例。结果：ＣＮＧ组与Ｃｉｔ组显效率分别为７３％和５４％（Ｐ＜０．０５），未见明显不良反应。结论：ＣＮＧ是治疗急性期脑出血所致神经功能障碍安全有效的新药
Objective: To compare the efficacy of cranial nerve growth factor (CNG) and citicoline (Cit) in the treatment of neurological dysfunction caused by acute cerebral hemorrhage. Methods: 56 cases in CNG group (32 males and 24 females; age (61 ± s5) a], course of disease (3.8 ± 1.5) d, bleeding volume (20.5 ± 2.3) mL; CNG 2 ~ 4mL, im, qd, medication 10 ~ 20d in 30 cases, 21 ~ 30d in 26 cases. Cit group 60 cases [38 males and 22 females; age (59 ± 9) a], course of disease (3.5 ± 1.7) d, bleeding volume (19.3 ± 2.8) mL; Cit500mg in 5 % Glucose injection 500mL intravenous drip, qd, medication 10 ~ 20d in 24 cases, 21 ~ 30d in 36 cases. Results: The markedly effective rates of CNG group and Cit group were 73% and 54% respectively (P <0.05), and no obvious adverse reactions were found. Conclusion: CNG is a safe and effective new drug for the treatment of neurological dysfunction caused by cerebral hemorrhage in acute stage