重症急性胰腺炎(severe acute pancreatitis,SAP)是临床常见胃肠道危重疾病,可以导致全身多脏器功能障碍,具有并发症多、住院时间长、病死率高、社会经济负担重等特点~([1])。文献报道SAP病死率达30%~50%~([2-3])。当前,SAP的处理仍无特异性的切实有效的治疗方法,但近年来一系列的治疗理念的推广、治疗干预的实施大大降低了病人的病死率,这些措施包括液体复苏、镇静镇痛、微创引 Severe acute pancreatitis (SAP) is a common clinical critical gastrointestinal disease, which can lead to multiple organ dysfunction, multiple complications, long hospital stay, high mortality and heavy socioeconomic burden. [1]). Reported in the literature SAP mortality rate of 30% to 50% ~ ([2-3]). At present, there is still no specific and effective treatment for SAP. However, promotion of a series of treatment concepts and treatment interventions in recent years has greatly reduced patient mortality. These measures include liquid resuscitation, sedation and analgesia, micro Created