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对甲醛暴露的小鼠脾淋巴细胞转化反应及ＩＬ２活性水平进行了研究，在０．０５ｍｇ／ｍ３、０．１０ｍｇ／ｍ３、２．０ｍｇ／ｍ３、３．０ｍｇ／ｍ３甲醛浓度下，小鼠脾淋巴细胞对ＣｏｎＡ的转化反应逐渐受到抑制，抑制率分别为１．６５％、３．０３％、２５．７４％、３５．６４％；ＩＬ２活性也受到相应的抑制，其抑制率分别为１．０７％、１．６９％、１９．８０％、３１．４０％。用维生素Ａ在体外进行营养干预，其最适浓度分别为２．５×１０－８ｍｏｌ／Ｌ，５．０×１０－８ｍｏｌ／Ｌ，１．０×１０－７ｍｏｌ／Ｌ，７．５×１０－６ｍｏｌ／Ｌ，可拮抗不同浓度甲醛暴露小鼠脾淋巴细胞转化反应和ＩＬ２活性水平，效果显著。
Formaldehyde-exposed mouse spleen lymphocyte transformation and IL 2 activity were studied at 0.05mg / m3, 0.10mg / m3, 2.0mg / m3, 3.0mg / m3 formaldehyde concentration, small ConA transformation of mouse spleen lymphocytes gradually inhibited, the inhibition rates were 1.65%, 3.03%, 25.74%, 35.64%; IL 2 activity was also inhibited, the inhibition rate Respectively 1.07%, 1.69%, 19.80%, 31.40%. With vitamin A nutrition intervention in vitro, the optimum concentrations were 2.5 × 10-8mol / L, 5.0 × 10-8mol / L, 1.0 × 10-7mol / L, 7.5 × 10 -6mol / L, can antagonize the different concentrations of formaldehyde exposure mice splenic lymphocyte transformation and IL 2 activity levels, the effect is significant.